PUBLICATIONS
Advancing Knowledge in Metabolic Networks
2024
2023
•Zimatore, G.; Serantoni, C.; Gallotta, M.C.; Guidetti, L.; Maulucci, G.; De Spirito, M. Automatic Detection of Aerobic Threshold through Recurrence Quantification Analysis of Heart Rate Time Series. International Journal of Environmental Research and Public Health 2023, 20, 1998. (DOI: 10.3390/ijerph20031998)
•Mancini, F.; Di Nicuolo, F.; Teveroni, E.; Vergani, E.; Bianchetti, G.; Bruno, C.; Grande, G.; Iavarone, F.; Maulucci, G.; De Spirito, M.; Urbani, A.; Pontecorvi, A.; Milardi, D. Combined evaluation of prolactin-induced peptide (PIP) and extracellular signal-regulated kinase (ERK) as new sperm biomarkers of FSH treatment efficacy in normogonadotropic idiopathic infertile men. Journal of Endocrinological Investigation 2023, 47, 455–468. (DOI: 10.1007/s40618-023-01919-w)
•Bianco, D.M.; De Maio, F.; Santarelli, G.; Palucci, I.; Salustri, A.; Bianchetti, G.; Maulucci, G.; Citterio, F.; Sanguinetti, M.; Tamburrini, E.; Sali, M.; Delogu, G. Evaluation of Everolimus Activity against Mycobacterium tuberculosis Using In Vitro Models of Infection. Antibiotics 2023, 12, 171. (DOI: 10.3390/antibiotics12020171)
•Riente, A.; Abeltino, A.; Serantoni, C.; Bianchetti, G.; De Spirito, M.; Capezzone, S.; Esposito, R.; Maulucci, G. Evaluation of the Chewing Pattern through an Electromyographic Device. Biosensors 2023, 13, 749. (DOI: 10.3390/bios13080749)
•Bianchetti, G.; Clementi, M.E.; Sampaolese, B.; Serantoni, C.; Abeltino, A.; De Spirito, M.; Sasson, S.; Maulucci, G. Metabolic Imaging and Molecular Biology Reveal the Interplay between Lipid Metabolism and DHA-Induced Modulation of Redox Homeostasis in RPE Cells. Antioxidants 2023, 12, 339. (DOI: 10.3390/antiox12020339)
•Abeltino, A.; Bianchetti, G.; Bianchetti, G.; Serantoni, C.; Riente, A.; De Spirito, M.; Maulucci, G. Putting the Personalized Metabolic Avatar into Production: A Comparison between Deep-Learning and Statistical Models for Weight Prediction. Nutrients 2023, 15, 1199. (DOI: 10.3390/nu15051199)
•Testa, E.; Panzeri, V.; Rizzolio, S.; Bianchetti, G.; Napolitano, V.; Fazi, F.; Maulucci, G.; Scicchitano, B.M.; Sette, C.; Viscomi, M.T.; Tamagnone, L. SEMA6C: a novel adhesion-independent FAK and YAP activator, required for cancer cell viability and growth. Cellular and Molecular Life Sciences 2023, 80, 155 (15 pages). (DOI: 10.1007/s00018-023-04856-z)
•Teveroni, E.; Di Nicuolo, F.; Vergani, E.; Oliva, A.; Vodola, E.P.; Bianchetti, G.; Maulucci, G.; De Spirito, M.; Cenci, T.; Pierconti, F.; Gulino, G.; Iavarone, F.; Urbani, A.; Milardi, D.; Pontecorvi, A.; Mancini, F. SPTBN1 Mediates the Cytoplasmic Constraint of PTTG1, Impairing Its Oncogenic Activity in Human Seminoma. International Journal of Molecular Sciences 2023, 24, 5583. (DOI: 10.3390/ijms24065583)
•Bianchetti, G.; De Maio, F.; Abeltino, A.; Serantoni, C.; Riente, A.; Santarelli, G.; Sanguinetti, M.; Delogu, G.; Martinoli, R.; Barbaresi, S.; De Spirito, M.; Maulucci, G. Unraveling the Gut Microbiome–Diet Connection: Exploring the Impact of Digital Precision and Personalized Nutrition on Microbiota Composition and Host Physiology. Nutrients 2023, 15, 2770. (DOI: 10.3390/nu15122770)
2022
•Bianchetti, G.; Taralli, S.; Vaccaro, M.; Indovina, L.; Mattoli, M.V.; Capotosti, A.; Scolozzi, V.; Calcagni, M.L.; Giordano, A.; De Spirito, M.; Maulucci, G. Automated detection and classification of tumor histotypes on dynamic PET imaging data through machine-learning driven voxel classification. Computers in Biology and Medicine 2022, 145, 105423. (DOI: 10.1016/j.compbiomed.2022.105423)
•Clementi, M.E.; Pizzoferrato, M.; Bianchetti, G.; Brancato, A.; Sampaolese, B.; Maulucci, G.; Tringali, G. Cytoprotective Effect of Idebenone through Modulation of the Intrinsic Mitochondrial Pathway of Apoptosis in Human Retinal Pigment Epithelial Cells Exposed to Oxidative Stress Induced by Hydrogen Peroxide. Biomedicines 2022, 10, 503–517. (DOI: 10.3390/biomedicines10030503)
•Zimatore, G.; Gallotta, M.C.; Campanella, M.; Campanella, M.G.; Skarzynski, P.H.; Maulucci, G.; Serantoni, C.; De Spirito, M.; Curzi, D.; Guidetti, L.; Baldari, C.; Hatzopoulos, S. Detecting Metabolic Thresholds from Nonlinear Analysis of Heart Rate Time Series: A Review. International Journal of Environmental Research and Public Health 2022, 19, 12719. (DOI: 10.3390/ijerph191912719)
•Bianchetti, G.; Clementi, M.E.; Sampaolese, B.; Serantoni, C.; Abeltino, A.; De Spirito, M.; Sasson, S.; Maulucci, G. Investigation of DHA-Induced Regulation of Redox Homeostasis in Retinal Pigment Epithelium Cells through the Combination of Metabolic Imaging and Molecular Biology. Antioxidants 2022, 11, 1072. (DOI: 10.3390/antiox11061072)
•Abeltino, A.; Bianchetti, G.; Serantoni, C.; Ardito, C.F.; Malta, D.; De Spirito, M.; Maulucci, G. Personalized Metabolic Avatar: A Data Driven Model of Metabolism for Weight Variation Forecasting and Diet Plan Evaluation. Nutrients 2022, 14, 3520. (DOI: 10.3390/nu14173520)
•Bianchetti, G.; Bianchetti, G.; Abeltino, A.; Serantoni, C.; Ardito, F.; Malta, D.; De Spirito, M.; Maulucci, G. Personalized Self-Monitoring of Energy Balance through Integration in a Web-Application of Dietary, Anthropometric, and Physical Activity Data. Journal of Personalized Medicine 2022, 12, 568. (DOI: 10.3390/jpm12040568)
•Cavallucci, V.; Palucci, I.; Fidaleo, M.; Mercuri, A.; Masi, L.; Emoli, V.; Bianchetti, G.; Fiori, M.E.; Bachrach, G.; Scaldaferri, F.; Maulucci, G.; Delogu, G.; Pani, G. Proinflammatory and cancer-promoting pathobiont Fusobacterium nucleatum directly targets colorectal cancer stem cells. Biomolecules 2022, 12, 1256. (DOI: 10.3390/biom12091256)
•Teveroni, E.; Di Nicuolo, F.; Vergani, E.; Bruno, C.; Bianchetti, G.; Maulucci, G.; De Spirito, M.; Cenci, T.; Pierconti, F.; Gulino, G.; Iavarone, F.; Urbani, A.; Milardi, D.; Pontecorvi, A.; Mancini, F. PTTG1/ZEB1 Axis Regulates E-Cadherin Expression in Human Seminoma. Cancers 2022, 14, 5280. (DOI: 10.3390/cancers14215280)
•Bianchetti, G.; Rizzo, G.E.; Serantoni, C.; Abeltino, A.; Rizzi, A.; Tartaglione, L.; Caputo, S.; Flex, A.; De Spirito, M.; Pitocco, D.; Maulucci, G. Spatial Reorganization of Liquid Crystalline Domains of Red Blood Cells in Type 2 Diabetic Patients with Peripheral Artery Disease. International Journal of Molecular Sciences 2022, 23, 11126–11138. (DOI: 10.3390/ijms230211126)
•Serantoni, C.; Zimatore, G.; Bianchetti, G.; Abeltino, A.; De Spirito, M.; Maulucci, G. Unsupervised Clustering of Heartbeat Dynamics Allows for Real Time and Personalized Improvement in Cardiovascular Fitness. Sensors 2022, 22, 3974. (DOI: 10.3390/s22113974)
2021
•Clementi, M.E.; Maulucci, G.; Bianchetti, G.; Pizzoferrato, M.; Sampaolese, B.; Tringali, G. Cytoprotective effects of punicalagin on hydrogen-peroxide–mediated oxidative stress and mitochondrial dysfunction in retinal pigment epithelium cells. Antioxidants 2021, 10, 995. (DOI: 10.3390/antiox10060995)
•Bianchetti, G.; Bianchetti, G.; Viti, L.; Scupola, A.; Di Leo, M.; Tartaglione, L.; Flex, A.; De Spirito, M.; Pitocco, D.; Maulucci, G. Erythrocyte membrane fluidity as a marker of diabetic retinopathy in type 1 diabetes mellitus. European Journal of Clinical Investigation 2021, 51, e13455. (DOI: 10.1111/eci.13455)
•Bianchetti, G.; Azoulay-Ginsburg, S.; Keshet-Levy, N.Y.; Malka, A.; Zilber, S.; Korshin, E.E.; Sasson, S.; De Spirito, M.; Gruzman, A.; Maulucci, G. Investigation of the membrane fluidity regulation of fatty acid intracellular distribution by fluorescence lifetime imaging of novel polarity-sensitive fluorescent derivatives. International Journal of Molecular Sciences 2021, 22, 7519. (DOI: 10.3390/ijms22147519)
•Bianchetti, G.; Bianchetti, G.; Ciccarone, F.; Ciriolo, M.R.; De Spirito, M.; Pani, G.; Maulucci, G. Label-free metabolic clustering through unsupervised pixel classification of multiparametric fluorescent images. Analytica Chimica Acta 2021, 1148, 238173. (DOI: 10.1016/j.aca.2021.238173)
2020
•Ciccarone, F.; Di Leo, L.; Lazzarino, G.; Maulucci, G.; Di Giacinto, F.; Tavazzi, B.; Ciriolo, M.R. Aconitase 2 inhibits the proliferation of MCF-7 cells promoting mitochondrial oxidative metabolism and ROS/FoxO1-mediated autophagic response. British Journal of Cancer 2020, 122, 182–193. (DOI: 10.1038/s41416-019-0664-1)
•Nobile, V.; Palumbo, F.; Lanni, S.; Ghisio, V.; Vitali, A.; Castagnola, M.; Marzano, V.; Maulucci, G.; De Angelis, C.; De Spirito, M.; Pacini, L.; D’Andrea, L.; D’Andrea, G.; Ragno, R.; Stazi, G.; Valente, S.; Mai, A.; Chiurazzi, P.; Genuardi, M.; Neri, G.; Tabolacci, E. Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene. Human Genetics 2020, 139, 227–245. (DOI: 10.1007/s00439-019-02100-x)
•Palucci, I.; Maulucci, G.; De Maio, F.; Sali, M.; Romagnoli, A.; Petrone, L.; Fimia, G.M.; Sanguinetti, M.; Goletti, D.; De Spirito, M.; Piacentini, M.; Delogu, G. Inhibition of Transglutaminase 2 as a Potential Host-Directed Therapy Against Mycobacterium tuberculosis. Frontiers in Immunology 2020, 10, 3042. (DOI: 10.3389/fimmu.2019.03042)
•Bianchetti, G.; Bianchetti, G.; Di Giacinto, F.; De Spirito, M.; Maulucci, G. Machine-learning assisted confocal imaging of intracellular sites of triglycerides and cholesteryl esters formation and storage. Analytica Chimica Acta 2020, 1121, 57–66. (DOI: 10.1016/j.aca.2020.05.045)
•Bianchetti, G.; De Spirito, M.; Maulucci, G. Unsupervised clustering of multiparametric fluorescent images extends the spectrum of detectable cell membrane phases with sub-micrometric resolution. Biomedical Optics Express 2020, 11, 5728–5744. (DOI: 10.1364/BOE.402898)
2019
•Perini, G.; Ciasca, G.; Minelli, E.; Papi, M.; Palmieri, V.; Maulucci, G.; Nardini, M.; Latina, V.; Corsetti, V.; Florenzano, F.; Calissano, P.; De Spirito, M.; Amadoro, G. Dynamic structural determinants underlie the neurotoxicity of the N-terminal tau 26–44 peptide in Alzheimer’s disease and other human tauopathies. International Journal of Biological Macromolecules 2019, 141, 278–289. (DOI: 10.1016/j.ijbiomac.2019.08.256)
•Scanferlato, R.; Bortolotti, M.; Sansone, A.; Chatgilialoglu, C.; Polito, L.; De Spirito, M.; Maulucci, G.; Bolognesi, A.; Ferreri, C. Hexadecenoic Fatty Acid Positional Isomers and De Novo PUFA Synthesis in Colon Cancer Cells. International Journal of Molecular Sciences 2019, 20, 832. (DOI: 10.3390/ijms20040832)
•Xepapadaki, E.; Maulucci, G.; Constantinou, C.; Karavia, E.A.; Zvintzou, E.; Daniel, B.; Sasson, S.; Kypreos, K.E. Impact of apolipoprotein A1- or lecithin:cholesterol acyltransferase-deficiency on white adipose tissue metabolic activity and glucose homeostasis in mice. Biochimica et Biophysica Acta – Molecular Basis of Disease 2019, 1865, 1351–1360. (DOI: 10.1016/j.bbadis.2019.04.005)
•Di Giacinto, F.; De Spirito, M.; Maulucci, G. Low-Intensity Ultrasound Induces Thermodynamic Phase Separation of Cell Membranes through a Nucleation–Condensation Process. Ultrasound in Medicine and Biology 2019, 45, 1143–1150. (DOI: 10.1016/j.ultrasmedbio.2019.01.003)
•Bianchetti, G.; Bianchetti, G.; Di Giacinto, F.; Pitocco, D.; Rizzi, A.; Rizzo, G.E.; De Leva, F.; Flex, A.; Di Stasio, E.; Ciasca, G.; De Spirito, M.; Maulucci, G. Red blood cells membrane micropolarity as a novel diagnostic indicator of type 1 and type 2 diabetes. Analytica Chimica Acta: X 2019, 3, 100030. (DOI: 10.1016/j.acax.2019.100030)
•Maulucci, G.; Cohen, O.; Daniel, B.; Ferreri, C.; Sasson, S. The combination of whole cell lipidomics analysis and single cell confocal imaging of fluidity and micropolarity provides insight into stress-induced lipid turnover in subcellular organelles of pancreatic beta cells. Molecules 2019, 24, 1900 (1–13). (DOI: 10.3390/molecules24101900)
2018
•Cordelli, E.; Maulucci, G.; De Spirito, M.; Rizzi, A.; Pitocco, D.; Soda, P. A decision support system for type 1 diabetes mellitus diagnostics based on dual channel analysis of red blood cell membrane fluidity. Computer Methods and Programs in Biomedicine 2018, 162, 263–271. (DOI: 10.1016/j.cmpb.2018.05.017)
•Minelli, E.; Sassun, T.E.; Papi, M.; Palmieri, V.; Palermo, F.; Perini, G.; Antonelli, M.; Gianno, F.; Maulucci, G.; Ciasca, G.; De Spirito, M. Nanoscale mechanics of brain abscess: An atomic force microscopy study. Micron 2018, 113, 34–40. (DOI: 10.1016/j.micron.2018.06.002)
•Maulucci, G.; Di Giacinto, F.; De Angelis, C.; Cohen, O.; Daniel, B.; Ferreri, C.; De Spirito, M.; Sasson, S. Real time quantitative analysis of lipid storage and lipolysis pathways by confocal spectral imaging of intracellular micropolarity. Biochimica et Biophysica Acta – Molecular and Cell Biology of Lipids 2018, 1863, 783–793. (DOI: 10.1016/j.bbalip.2018.04.005)
•Crociati, M.; Di Giacinto, F.; Manuali, E.; Stradaioli, G.; Sylla, L.; Monaci, M.; Maulucci, G.; De Spirito, M. Systemic profiling of ectopic fat deposits in the reproductive tract of dairy cows. Theriogenology 2018, 114, 46–53. (DOI: 10.1016/j.theriogenology.2018.03.030)
•Palucci, I.; Matic, I.; Falasca, L.; Minerva, M.; Maulucci, G.; De Spirito, M.; Petruccioli, E.; Goletti, D.; Rossin, F.; Piacentini, M.; Delogu, G. Transglutaminase type 2 plays a key role in the pathogenesis of Mycobacterium tuberculosis infection. Journal of Internal Medicine 2018, 283, 303–313. (DOI: 10.1111/joim.12633)
2017
•Minelli, E.; Ciasca, G.; Sassun, T.E.; Antonelli, M.; Palmieri, V.; Papi, M.; Maulucci, G.; Santoro, A.; Giangaspero, F.; Delfini, R.; Campi, G.; De Spirito, M. A fully-automated neural network analysis of AFM force-distance curves for cancer tissue diagnosis. Applied Physics Letters 2017, 111, 143701. (DOI: 10.1063/1.4998401)
•Palmieri, V.; Bozzi, M.; Signorino, G.; Papi, M.; De Spirito, M.; Brancaccio, A.; Maulucci, G.; Sciandra, F. α-Dystroglycan hypoglycosylation affects cell migration by influencing β-dystroglycan membrane clustering and filopodia length: A multiscale confocal microscopy analysis. Biochimica et Biophysica Acta – Molecular Basis of Disease 2017, 1863, 2182–2191. (DOI: 10.1016/j.bbadis.2017.07.014)
•Maulucci, G.; Cordelli, E.; Rizzi, A.; De Leva, F.; Papi, M.; Ciasca, G.; Samengo, D.M.; Pani, G.; Pitocco, D.; Soda, P.; Ghirlanda, G.; Iannello, G.; De Spirito, M. Phase separation of the plasma membrane in human red blood cells as a potential tool for diagnosis and progression monitoring of type 1 diabetes mellitus. PLoS ONE 2017, 12, e0184109. (DOI: 10.1371/journal.pone.0184109)
2016
•Maulucci, G.; De Spirito, M. Imaging ROS-induced modifications in living systems. Antioxidants & Redox Signaling 2016, 24, 939–958. (DOI: 10.1089/ars.2015.6538)•Tersigni, C.; Di Nicuolo, F.; Maulucci, G.; Rolfo, A.; Giuffrida, D.; Veglia, M.; De Spirito, M.; Scambia, G.; Todros, T.; Di Simone, N. Placental chemokine receptor D6 is functionally impaired in pre-eclampsia. PLoS ONE 2016, 11, e0156065. (DOI: 10.1371/journal.pone.0156065)
•Ciasca, G.; Papi, M.; Businaro, L.; Campi, G.; Ortolani, M.; Palmieri, V.; Cedola, A.; De Ninno, A.; Gerardino, A.; Maulucci, G.; De Spirito, M. Recent advances in superhydrophobic surfaces and their relevance to biology and medicine. Bioinspiration & Biomimetics 2016, 11, 051001. (DOI: 10.1088/1748-3190/11/5/051001)
•Palmieri, V.; Papi, M.; Conti, C.; Ciasca, G.; Maulucci, G.; De Spirito, M. The future development of bacteria-fighting medical devices: the role of graphene oxide. Expert Review of Medical Devices 2016, 13, 1013–1019. (DOI: 10.1080/17434440.2016.1232162)
2015
•Bugli, F.; Papi, M.; Ciasca, G.; Maulucci, G.; Palmieri, V.; Cacaci, M.; Posteraro, B.; Sanguinetti, M.; De Spirito, M. Effect of Alginate Lyase on Biofilm-Grown Helicobacter pylori Probed by Atomic Force Microscopy. International Journal of Polymer Science 2015, 2015, Article ID 163506 (3 pages). (DOI: 10.1155/2015/163506)
•Veglia, M.; D’Ippolito, S.; Marana, R.; Di Nicuolo, F.; Castellani, R.; Bruno, V.; Fiorelli, A.; Ria, F.; Maulucci, G.; De Spirito, M.; Migliara, G.; Scambia, G.; Di Simone, N. Human IgG antinuclear antibodies induce pregnancy loss in mice by increasing immune complex deposition in placental tissue: In vivo study. American Journal of Reproductive Immunology 2015, 74, 542–552. (DOI: 10.1111/aji.12432)
•Ciasca, G.; Papi, M.; Di Claudio, S.; Chiarpotto, M.; Palmieri, V.; Maulucci, G.; Nocca, G.; Rossi, C.; De Spirito, M. Mapping viscoelastic properties of healthy and pathological red blood cells at the nanoscale level. Nanoscale 2015, 7, 17030–17037. (DOI: 10.1039/C5NR04435C)
•Palmieri, V.; Lucchetti, D.; Maiorana, A.; Papi, M.; Maulucci, G.; Calapà, F.; Ciasca, G.; Giordano, R.; Sgambato, A.; De Spirito, M. Mechanical and structural comparison between primary tumor and lymph node metastasis cells in colorectal cancer. Soft Matter 2015, 11, 5719–5726. (DOI: 10.1039/C5SM01089F)
•Papi, M.; Lauriola, M.C.; Palmieri, V.; Ciasca, G.; Maulucci, G.; De Spirito, M. Plasma protein corona reduces the haemolytic activity of graphene oxide nano and micro flakes. RSC Advances 2015, 5, 81638–81641. (DOI: 10.1039/C5RA14418J)
•Maulucci, G.; Chiarpotto, M.; Papi, M.; Samengo, D.M.; Pani, G.; De Spirito, M. Quantitative analysis of autophagic flux by confocal pH-imaging of autophagic intermediates. Autophagy 2015, 11, 1905–1916. (DOI: 10.1080/15548627.2015.1075117)
•Angelucci, C.; Maulucci, G.; Colabianchi, A.; Iacopino, F.; D’Alessio, A.; Maiorana, A.; Palmieri, V.; Papi, M.; De Spirito, M.; Di Leone, A.; Masetti, R.; Sica, G. Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts. British Journal of Cancer 2015, 112, 1675–1686. (DOI: 10.1038/bjc.2015.123)
•Tesori, V.; Piscaglia, A.C.; Samengo, D.; Barba, M.; Bernardini, C.; Scatena, R.; Pontoglio, A.; Castellini, L.; Spelbrink, J.N.; Maulucci, G.; Puglisi, M.A.; Pani, G.; Gasbarrini, A. The multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing. Scientific Reports 2015, 5, 9149. (DOI: 10.1038/srep09149)
2014
•Palmieri, V.; Lucchetti, D.; Maiorana, A.; Papi, M.; Maulucci, G.; Ciasca, G.; Svelto, M.; De Spirito, M.; Sgambato, A. Biomechanical investigation of colorectal cancer cells. Applied Physics Letters 2014, 105, 123701. (DOI: 10.1063/1.4896161)
•Palmieri, V.; Lucchetti, D.; Gatto, I.; Maiorana, A.; Marcantoni, M.; Maulucci, G.; Papi, M.; Pola, R.; De Spirito, M.; Sgambato, A. Dynamic light scattering for the characterization and counting of extracellular vesicles: a powerful noninvasive tool. Journal of Nanoparticle Research 2014, 16, 2583. (DOI: 10.1007/s11051-014-2583-z)
•De Maio, F.; Maulucci, G.; Minerva, M.; Anoosheh, S.; Palucci, I.; Iantomasi, R.; Palmieri, V.; Camassa, M.S.; Sali, M.; Sanguinetti, M.; Bitter, W.; Manganelli, R.; De Spirito, M.; Delogu, G. Impact of protein domains on PE_PGRS30 polar localization in mycobacteria. PLoS ONE 2014, 9, e112482. (DOI: 10.1371/journal.pone.0112482)
•Maulucci, G.; Maiorana, A.; Papi, M.; Pani, G.; De Spirito, M. Quantitative assessment of the relationship between cellular morphodynamics and signaling events by stochastic analysis of fluorescent images. Microscopy and Microanalysis 2014, 20, 1198–1207. (DOI: 10.1017/S1431927614001139)
•Maulucci, G.; Troiani, D.; Eramo, S.L.M.; Paciello, F.; Podda, M.V.; Paludetti, G.; Papi, M.; Maiorana, A.; Palmieri, V.; De Spirito, M.; Fetoni, A.R. Time evolution of noise-induced oxidation in outer hair cells: Role of NAD(P)H and plasma membrane fluidity. Biochimica et Biophysica Acta – General Subjects 2014, 1840, 2192–2202. (DOI: 10.1016/j.bbagen.2014.02.011)
2013
•Maiorana, A.; Papi, M.; Bugli, F.; Torelli, R.; Maulucci, G.; Cacaci, M.; Posteraro, B.; Sanguinetti, M.; De Spirito, M. A fast and quantitative evaluation of the Aspergillus fumigatus biofilm adhesion properties by means of digital pulsed force mode. Applied Surface Science 2013, 285, 409–415. (DOI: 10.1016/j.apsusc.2013.08.020)
•Lama, G.; Papi, M.; Angelucci, C.; Maulucci, G.; Sica, G.; De Spirito, M. Leuprorelin Acetate Long-Lasting Effects on GnRH Receptors of Prostate Cancer Cells: An Atomic Force Microscopy Study of Agonist/Receptor Interaction. PLoS ONE 2013, 8, e52530. (DOI: 10.1371/journal.pone.0052530)
•Di Simone, N.; De Spirito, M.; Di Nicuolo, F.; Tersigni, C.; Castellani, R.; Silano, M.; Maulucci, G.; Papi, M.; Marana, R.; Scambia, G.; Gasbarrini, A. Potential new mechanisms of placental damage in celiac disease: anti-transglutaminase antibodies impair human endometrial angiogenesis. Biology of Reproduction 2013, 89, 88. (DOI: 10.1095/biolreprod.113.109637)
•Papi, M.; Maiorana, A.; Douet, C.; Maulucci, G.; Parasassi, T.; Brunelli, R.; Goudet, G.; De Spirito, M. Viscous forces are predominant in the zona pellucida mechanical resistance. Applied Physics Letters 2013, 102, 043703. (DOI: 10.1063/1.4789500)
•Palmieri, V.; Maulucci, G.; Maiorana, A.; Papi, M.; De Spirito, M. α-Crystallin Modulates its Chaperone Activity by Varying the Exposed Surface. ChemBioChem 2013, 14, 2362–2370. (DOI: 10.1002/cbic.201300382)
2012
•Papi, M.; Maiorana, A.; Bugli, F.; Torelli, R.; Posteraro, B.; Maulucci, G.; De Spirito, M.; Sanguinetti, M. Detection of biofilm-grown Aspergillus fumigatus by means of atomic force spectroscopy: ultrastructural effects of alginate lyase. Microscopy and Microanalysis 2012, 18, 1088–1094. (DOI: 10.1017/S143192761200196X)
•Angelucci, C.; Maulucci, G.; Lama, G.; Proietti, G.; Colabianchi, A.; Papi, M.; Maiorana, A.; De Spirito, M.; Masetti, R.; Sica, G. Epithelial–stromal interactions in human breast cancer: effects on adhesion, plasma membrane fluidity and migration speed and directness. PLoS ONE 2012, 7, e40338. (DOI: 10.1371/journal.pone.0040338)
•Greco, E.; Quintiliani, G.; Santucci, M.B.; Serafino, A.; Ciccaglione, A.R.; Marcantonio, C.; Papi, M.; Maulucci, G.; Delogu, G.; Martino, A.; Goletti, D.; Sarmati, L.; Andreoni, M.; Altieri, A.; Alma, M.; Caccamo, N.; Di Liberto, D.; De Spirito, M.; Savage, N.D.; Nisini, R.; Dieli, F.; Ottenhoff, T.H.; Fraziano, M. Janus-faced liposomes enhance antimicrobial innate immune response in Mycobacterium tuberculosis infection. Proceedings of the National Academy of Sciences USA 2012, 109, E1360–E1368. (DOI: 10.1073/pnas.1118131109)
•Boccaccio, A.; Frassanito, M.C.; Lamberti, L.; Brunelli, R.; Maulucci, G.; Monaci, M.; Papi, M.; Pappalettere, C.; Parasassi, T.; Sylla, L.; Ursini, F.; De Spirito, M. Nanoscale characterization of the biomechanical hardening of bovine zona pellucida. Journal of the Royal Society Interface 2012, 9, 2871–2882. (DOI: 10.1098/rsif.2012.0322)
•Iantomasi, R.; Sali, M.; Cascioferro, A.; Palucci, I.; Zumbo, A.; Soldini, S.; Rocca, S.; Greco, E.; Maulucci, G.; De Spirito, M.; Fraziano, M.; Fadda, G.; Manganelli, R.; Delogu, G. PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosis. Cellular Microbiology 2012, 14, 356–367. (DOI: 10.1111/j.1462-5822.2011.01729.x)
•Fusco, S.; Maulucci, G.; Pani, G. Sirt1: Def-eating senescence? Cell Cycle 2012, 11, 4135–4146. (DOI: 10.4161/cc.22559)•Maulucci, G.; Papi, M.; Arcovito, G.; De Spirito, M. The Thermal Structural Transition of α-Crystallin Modulates Subunit Interactions and Increases Protein Solubility. PLoS ONE 2012, 7, e37242. (DOI: 10.1371/journal.pone.0037242)
•Papi, M.; Brunelli, R.; Familiari, G.; Frassanito, M.C.; Lamberti, L.; Maulucci, G.; Monaci, M.; Pappalettere, C.; Parasassi, T.; Relucenti, M.; Sylla, L.; Ursini, F.; De Spirito, M. Whole-depth change in bovine zona pellucida biomechanics after fertilization: how relevant in hindering polyspermy? PLoS ONE 2012, 7, e45696. (DOI: 10.1371/journal.pone.0045696)
2011
•Papi, M.; Palmieri, V.; Maulucci, G.; Arcovito, G.; Greco, E.; Quintiliani, G.; Fraziano, M.; De Spirito, M. Controlled self assembly of collagen nanoparticle. Journal of Nanoparticle Research 2011, 13, 6141–6147. (DOI: 10.1007/s11051-011-4492-9)
•Balogh, G.; Maulucci, G.; Gombos, I.; Horváth, I.; Török, Z.; Péter, M.; Fodor, E.; Páli, T.; Benko, S.; Parasassi, T.; De Spirito, M.; Harwood, J.L.; Vígh, L. Heat stress causes spatially-distinct membrane re-modelling in K562 leukemia cells. PLoS ONE 2011, 6, e21182. (DOI: 10.1371/journal.pone.0021182)
•De Spirito, M.; Missori, M.; Maulucci, G.; Teixeira, J.; Papi, M. Nanocavities trapped along fibrin fibers allow the diffusion of thrombolytic drugs. Applied Physics Letters 2011, 98, 203701. (DOI: 10.1063/1.3587162)
•Papi, M.; De Spirito, M.; Maulucci, G. The Thermal Structural Transition of α-Crystallin Inhibits the Heat Induced Self-Aggregation. PLoS ONE 2011, 6, e18906. (DOI: 10.1371/journal.pone.0018906)
2010
•Papi, M.; De Spirito, M.; Maulucci, G. Can redox-sensitive fluorescent probes measure intracellular redox potentials? Il Nuovo Cimento B 2010, 125, 645–655. (DOI: 10.1393/ncb/i2010-10936-6)
•Missori, M.; Papi, M.; Maulucci, G.; Arcovito, G.; De Spirito, M. Cl<sup>−</sup> and F<sup>−</sup> anions regulate the architecture of protofibrils in fibrin gel. European Biophysics Journal 2010, 39, 1001–1006. (DOI: 10.1007/s00249-009-0492-3)
•Maulucci, G.; Pani, G.; Fusco, S.; Papi, M.; Arcovito, G.; Galeotti, T.; Fraziano, M.; De Spirito, M. Compartmentalization of the redox environment in PC-12 neuronal cells. European Biophysics Journal 2010, 39, 993–999. (DOI: 10.1007/s00249-009-0493-2)
•De Spirito, M.; Maulucci, G. Fluctuations and the Rate-Limiting Step of Peptide-Induced Membrane Leakage. Biophysical Journal 2010, 99, 1791–1800. (DOI: 10.1016/j.bpj.2010.06.067)
•Chiatamone Ranieri, S.; Fusco, S.; Panieri, E.; Mele, M.; Labate, V.; Tesori, V; Ferrara, A.M.; Maulucci, G.; De Spirito, M.; Martorana, G.E.; Galeotti, T.; Pani, G. Mammalian life-span determinant p66<sup>ShcA</sup> mediates obesity-induced insulin resistance. Proceedings of the National Academy of Sciences USA 2010, 107, 13420–13425. (DOI: 10.1073/pnas.1003775107)
•Papi, M.; Brunelli, R.; Sylla, L.; Parasassi, T.; Monaci, M.; Maulucci, G.; Missori, M.; Arcovito, G.; Ursini, F.; De Spirito, M. Mechanical properties of zona pellucida hardening. European Biophysics Journal 2010, 39, 987–992. (DOI: 10.1007/s00249-010-0582-2)
•Panieri, E.; Toietta, G.; Mele, M.; Labate, V.; Chiatamone Ranieri, S.; Fusco, S.; Tesori, V.; Antonini, A.; Maulucci, G.; De Spirito, M.; Galeotti, T.; Pani, G. Nutrient withdrawal rescues growth factor-deprived cells from mTOR-dependent damage. Aging 2010, 2, 487–503. (DOI: 10.18632/aging.100180)
•Papi, M.; Maulucci, G.; De Spirito, M.; Missori, M.; Arcovito, G.; Lancellotti, S.; Di Stasio, E.; De Cristofaro, R.; Arcovito, A. Ristocetin-induced self-aggregation of von Willebrand factor. European Biophysics Journal 2010, 39, 1597–1603. (DOI: 10.1007/s00249-010-0629-4)
2009
•Papi, M.; Sylla, L.; Parasassi, T.; Brunelli, R.; Monaci, M.; Maulucci, G.; Missori, M.; Arcovito, G.; Ursini, F.; De Spirito, M. Evidence of elastic to plastic transition in the zona pellucida of oocytes using atomic force spectroscopy. Applied Physics Letters 2009, 94, 153902. (DOI: 10.1063/1.3115044)
•Maulucci, G.; Pani, G.; Labate, V.; Mele, M.; Panieri, E.; Papi, M.; Arcovito, G.; Galeotti, T.; De Spirito, M. Investigation of the spatial distribution of glutathione redox-balance in live cells by using Fluorescence Ratio Imaging Microscopy. Biosensors & Bioelectronics 2009, 25, 682–687. (DOI: 10.1016/j.bios.2009.08.044)
2008
•Illario, M.; Giardino Torchia, M.; Sankar, U.; Ribar, T.; Galgani, M.; Vitiello, L.; Masci, A.; Bertani, F.; Ciaglia, E.; Astone, D.; Maulucci, G.; Cavallo, A.; Vitale, M.; Cimini, V.; Pastore, L.; Means, A.R.; Rossi, G.; Racioppi, L. Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells. Blood 2008, 111, 723–731. (DOI: 10.1182/blood-2007-07-101170)
•Papi, M.; Maulucci, G.; Arcovito, G.; Paoletti, P.; Vassalli, M.; De Spirito, M. Detection of microviscosity by using uncalibrated atomic force microscopy cantilevers. Applied Physics Letters 2008, 93, 124105. (DOI: 10.1063/1.2998592)
•Maulucci, G.; Labate, V.; Mele, M.; Panieri, E.; Arcovito, G.; Galeotti, T.; Østergaard, H.; Winther, J.R.; De Spirito, M.; Pani, G. High-resolution imaging of redox signaling in live cells through an oxidation-sensitive yellow fluorescent protein. Science Signaling 2008, 1(38), ra22 (14 pages). (DOI: 10.1126/scisignal.1160447)
•Parasassi, T.; De Spirito, M.; Mei, G.; Brunelli, R.; Greco, G.; Lenzi, L.; Maulucci, G.; Nicolai, E.; Papi, M.; Arcovito, G.; Tosatto, S.C.E.; Ursini, F. Low-density lipoprotein misfolding and amyloidogenesis. FASEB Journal 2008, 22, 2350–2356. (DOI: 10.1096/fj.07-099184)
•De Spirito, M.; Missori, M.; Papi, M.; Maulucci, G.; Teixeira, J.; Castellano, C.; Arcovito, G. Modifications in solvent clusters embedded along the fibers of a cellulose polymer network cause paper degradation. Physical Review E 2008, 77, 016110. (DOI: 10.1103/PhysRevE.77.016110)
•Koch, O.R.; Fusco, S.; Ranieri, S.C.; Maulucci, G.; Palozza, P.; Larocca, L.M.; Cravero, A.A.M.; Farrè, S.M.; De Spirito, M.; Galeotti, T.; Pani, G. Role of the life span determinant p66<sup>ShcA</sup> in ethanol-induced liver damage. Laboratory Investigation 2008, 88, 750–760. (DOI: 10.1038/labinvest.2008.47)